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Adipogen/anti-Glutaredoxin 1, mAb (28C3)/YIF-LF-MA0072/100 µl
Adipogen/anti-Glutaredoxin 1, mAb (28C3)/YIF-LF-MA0072/100 µl
商品编号：
YIF-LF-MA0072
品牌：
Adipogen Inc
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | GRX; GLRX; TTase-1; Glutaredoxin-1; Thioltransferase-1 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 28C3 |
| Isotype | Mouse IgG1 κ |
| Immunogen/Antigen | Recombinant human protein purified from E. coli. |
| Application |
ELISA Immunoprecipitation (1~2 μl) |
| Crossreactivity | Human |
| Purity Detail | Ammonium sulfate precipitation. |
| Formulation | Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| Declaration | Manufactured by AbFrontier |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH (1). First recovered in E.coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxido-reductase via two redox-active cysteine residues (2). The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12 kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress (3). Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Product References
1) Holmgren, A. (1990) p. 146-154, CRC Press Inc., Boca Raton, FL. (General)
2) Holmgren, A. (1989) J. Biol. Chem. 264, 13963-13966. (General)
3) Jung, C. H. and Thomas, J. A. (1996) Arch. Biochem. Biophys. 335, 61-72. (General)
2) Holmgren, A. (1989) J. Biol. Chem. 264, 13963-13966. (General)
3) Jung, C. H. and Thomas, J. A. (1996) Arch. Biochem. Biophys. 335, 61-72. (General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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