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Adipogen/anti-GITRL (mouse), pAb (Biotin)/AG-25A-0002B-C050/50 µg
Adipogen/anti-GITRL (mouse), pAb (Biotin)/AG-25A-0002B-C050/50 µg
商品编号：
AG-25A-0002B-C050
品牌：
Adipogen Inc
市场价：
¥4800.00
美元价：
2880.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Glucocorticoid-inducedTNFReceptorLigand;AITRL;Activation-inducIBLeTNF-relatedLigand;TNFSF18 |
| ProductType | PolyclonalAntibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | RecombinantmouseGITRL. |
| Label/Conjugates | Biotin |
| Application | ELISA:(directandindirect:1:5"000-1:10"000). FlowCytometry:(1:1"000). WesternBlot:(1:2"000-1:5"000usingECL.SuggestedblockinganddilutionbufferisTBSTwith0.05%Tween20with5%skimmilk.Suggestedincubationtimeis1houratroomtemperature). Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| Crossreactivity | Mouse |
| Specificity | RecognizesmouseGITRL.Doesnotcross-reactwithhumanGITRL. |
| PurityDetail | ProteinA-affinitypurified. |
| Concentration | 1mg/ml |
| Formulation | Liquid.0.2μm-filteredsolutioninPBS,pH7.4.Containsnopreservatives. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
GITRLisexpressedondendriticcells(DC),monocytes,macrophages,Bcells,activatedTcells,endothelialcells,osteoclastsandvarioushealthynon-lymphoidtissues(e.g.,testis,...).GITRLisconstitutivelyexpressedandreleasedassolubleformbysolidtumorsandvarioushematopoieticmalignancies.GITRLcausesdifferentiationofosteoclasts,activationofmacrophages,butalsoalterationofcarcinomaandleukemiacellsandinfluencesapoptosis.BindingtoGITRisimportantinregulatingT-cellproliferationandTCR-mediatedapoptosis.GITRLisimplicatedindevelopmentofautoimmunediseasesandintheimmuneresponseagainstinfectiouspathogensandtumors.
ProductReferences
- Identificationofaligandforglucocorticoid-inducedtumornecrosisfactorreceptorconstitutivelyexpressedindendriticcells:K.Y.Yu,etal.;BBRC310,433(2003)
- Thesolubleglucocorticoid-inducedtumornecrosisfactorreceptorcausescellcyclearrestandapoptosisinmurinemacrophages:H.H.Shin,etal.;BBRC316,24(2004)
- Solubleglucocorticoid-inducedtumornecrosisfactorreceptor(sGITR)stimulatesosteoclastdifferentiationinresponsetoreceptoractivatorofNF-kappaBligand(RANKL)inosteoclastcells:H.H.Shin,etal.;Bone36,832(2005)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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