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4000-520-616
当前位置: 首页 > 产品中心 > Functional_antibody > Adipogen/anti-GAPDH-SO3, mAb (4A1)/YIF-LF-MA0100/100 µl
商品详细Adipogen/anti-GAPDH-SO3, mAb (4A1)/YIF-LF-MA0100/100 µl
Adipogen/anti-GAPDH-SO3, mAb (4A1)/YIF-LF-MA0100/100 µl
Adipogen/anti-GAPDH-SO3, mAb (4A1)/YIF-LF-MA0100/100 µl
商品编号: YIF-LF-MA0100
品牌: Adipogen Inc
市场价: ¥6160.00
美元价: 3696.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsGAPD;GAPDH;CDABP0047;EC=2.6.99.-;EC=1.2.1.12;Peptidyl-CysteineS-NitrosylaseGAPDH;Glyceraldehyde-3-PhosphateDehydrogenase;Sulfonylated,Oxidized
ProductTypeMonoclonalAntibody
Properties
Clone4A1
IsotypeMouseIgG1κ
Immunogen/AntigenSulfonylatedpeptide(KLHcoupled)correspondingtotheoxidationsensitivesitesequencetohumanGAPDH.
ApplicationWesternBlot(1:200~1,000)
CrossreactivityHuman
PurityDetailAmmoniumsulfateprecipitation.
FormulationLiquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol.
OtherProductDataClickhereforOriginalManufacturerProductDatasheet
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
DeclarationManufacturedbyAbFrontier
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Documents
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
Glyceraldehyde-3-phosphatedehydrogenase(GAPDH)isacatalyticenzymecommonlyknowntobeinvolvedinglycolysis.Theenzymeexistsasatetramerofidentical37-kDasubunits.GAPDHcatalyzesthereversIBLereductionof1,3-bisphosphoglyceratetoglyceraldehyde3-phosphophateinthepresenceofNADPH.Apartfromplayingakeyroleinglycolysis,thisubiquitouslyexpressedenzymealsodisplaysotheractivitiesunrelatedtoitsglycolyticfunction.GAPDHisreportedtobeinvolvedintheprocessesofDNAreplication,DNArepair,nuclearRNAexport,membranefusionandmicrotubulebundling.OtherstudiesalsoprovideevidenceofGAPDHplayinganessentialpartoftheprogramofgeneexpressionobservedinapoptosisandaspartofthecellularphenotypeofage-relatedneurodegenerativediseases.Onrecentstudy,GAPDHhasidentifiedofthemostoxidantsensitivecellproteins.Independentofitsglycolyticactivityitisalsoinvolvedinmembranetraffickingintheearlysecretorypathway.
ProductReferences
1)Baxi,M.D.et.al.(1995)Biochemistry.34:9700-9707.(General)
2)Singh,R.et.al.(1993)Science.259:365-368.(General)
3)Han,X.et.al.(1998)Biochem.Biophys.Acta.1414:95-107.(General)
4)Kragten,E.et.al.(1998)J.Biol.Chem.273:5821-5828.(General)
5)Baty,J.W.et.al.(2005)BiochemJ.(General)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。