Adipogen/anti-Fis1, pAb/AG-25B-0007V-C100/100 µg
商品编号：
AG-25B-0007V-C100
品牌：
Adipogen Inc
市场价：
¥6400.00
美元价：
3840.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Mitochondrial Fission 1 Protein; Tetratricopeptide Repeat Protein 11; TTC 11 |
| Product Type | Polyclonal Antibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | Recombinant human Fis1. |
| Application |
Immunocytochemistry: (methanol fixation; 1:200) Immunoprecipitation: (1:200) Western Blot: (1:500) |
| Crossreactivity |
Human Mouse Rat |
| Specificity | Recognizes human, mouse and rat Fis1. |
| Purity Detail | Protein A-affinity purified. |
| Concentration | 1mg/ml |
| Formulation | Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. |
| Other Product Data | This purified antiserum is replacing the product AG-25B-0007 Fis-1 pAb (neat antiserum) with same specifications. |
| Declaration | Manufactured by AdipoGen. Formerly sold as ALX-210-907 by ALEXIS Biochemicals. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Fis1 promotes the fragmentation of the mitochondrial network and its perinuclear clustering. It can induce cytochrome c release from mitochondria to the cytosol, ultimately leading to apoptosis. It also mediates peroxisomal fission.
Product References
- hFis1, a novel component of the mammalian mitochondrial fission machinery: D.I. James, et al.; J. Biol. Chem. 278, 36373 (2003)
- A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells: A. Koch, et al.; Mol. Biol. Cell 16, 5077 (2005)
- The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells.: S. Gandre-Babbe & AM. van der Bliek; Mol. Biol. Cell 6, 2402 (2008)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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