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Adipogen/anti-Dibromo-tyrosine [DiBrY], mAb (3A5)/JAI-MBY-020P/20 µg
![Adipogen/anti-Dibromo-tyrosine [DiBrY], mAb (3A5)/JAI-MBY-020P/20 µg](https://www.ebiomall.cn/images/adipogen/jai-mby--ihc-2br_y_stain.jpg)
Adipogen/anti-Dibromo-tyrosine [DiBrY], mAb (3A5)/JAI-MBY-020P/20 µg
商品编号：
JAI-MBY-020P
品牌：
Adipogen Inc
市场价：
¥4600.00
美元价：
2760.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 3A5 |
| Isotype | Mouse IgG1κ |
| Immunogen/Antigen | Brominated keyhole limpet hemocyanin. |
| Application |
ELISA Immunohistochemistry: Recommended concentration is 10μg/mL Western Blot |
| Crossreactivity |
All Human |
| Specificity | Recognizes dibromotyrosine (DiBrY), N-acetylated dichloro tyrosine (NAcDiClY), diiodo tyrosine (DiIY), N-bromosuccinimide-treated BSA, HOCl-treated BSA and dibromo-tyrosone conjugated BSA (halogene-modified tyrosine at both 3- and 5-position). Does not cross-react with dityrosine-conjugated BSA, peroxynitrite-treated BSA, tyrosine (Y), chrolotyrosine(ClY), 3-3’-dityrosine (DiY), 3-aminotyrosine (NH2Y), 3-nitrotyrosine (NO2Y), phenylalanine (Phe), o-phosphotyrosine, 3,4-dihydroxyphenylacetic acid (DOPA) and 2-hydroxy-4-phenylacetic acid. Weakly cross-reacts with Bromotyrosine (BrY). |
| Purity Detail | Protein A purified. |
| Formulation | Lyophilized. Contains 10mM Phosphate buffered saline (pH7.4). |
| Reconstitution | Reconstitute with 200μL of distilled water. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| Declaration | Manufactured by JaICA. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| Protocols |
 Download PDF |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Neutrophils and eosinophils play an important role in the defence system against microbial infection. Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are known to catalyze formation of hypochlorous acid (HOCl) and hypobromous acid (HOBr). These reactive intermediates may react with proteins, lipids and nucleotides, and it has been reported to form tyrosine halogenation such as dibromotyrosine (DiBrY). DiBrY is a Br-modified tyrosine at 3- and 5- position, which is one of the major oxidative products derived from neutrophil myeloperoxidase. DiBrY may be a novel biomarker for tissue damage which is related to inflammatory and allergic disorders.
Product References
- Immunogenicity of a brominated protein and successive establishment of a monoclonal antibody to dihalogenated tyrosine: Y. Kato, et al.; Free Rad. Biol. Med. 38, 24 (2005)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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