脂肪原/抗细胞周期蛋白D3,pAb/YIF-LF-PA0053/100µl
商品编号:
YIF-LF-PA0053
品牌:
Adipogen Inc
市场价:
¥6160.00
美元价:
3696.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | CCND3; G1/S-specific Cyclin-D3 |
| Product Type | Polyclonal Antibody |
| Properties | |
| Immunogen/Antigen | Synthetic peptide. |
| Application |
Western Blot (1:2,000) Immunoprecipitation not tested. |
| Crossreactivity |
Human Mouse |
| Purity Detail | Protein A purified. |
| Formulation | Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| Declaration | Manufactured by AbFrontier |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Cyclin D3, ~34kDa, is a member of cyclin D family that promotes cell cycle progression to the DNA systhesis (S) phase. Cyclins complexed with cyclin-dependent kinases(CDKs) mediate phosphorylation of other proteins relevant to cell proliferation. D-type cyclins and their complexing CDKs phosphorylate the retinoblastoma gene product with influences transcription of growth-controlling genes. Cyclin D3 regulates cell proliferation during hematopoiesis, carcinogenesis, and may have function in the terminally differentiated cells. In recent studies, there is reports that cyclin D3 involves in multiple myeloma and malignant precursor T cells. Essential for the control of the cell cycle at the G1/S (start) transition. Potentiates the transcriptional activity of ATF5.
Product References
1) Watson DS et al, Oncology. 1999; vol.56(1): pp.66-72. (General)
2) Weng AP, Aster JC. Cancer Cell. 2003; vol.4(6): pp.451-61. (General)
3) Hideshima T et al, Blood. 2004; vol.104(3): pp.607-18. (General)
2) Weng AP, Aster JC. Cancer Cell. 2003; vol.4(6): pp.451-61. (General)
3) Hideshima T et al, Blood. 2004; vol.104(3): pp.607-18. (General)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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