脂肪原/抗CKII和β(酪蛋白激酶2（β），pAb/YIF-LF-PA0193/100µl
商品编号：
YIF-LF-PA0193
品牌：
Adipogen Inc
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | CK2N;CSNK2B;Phosvitin;CKIIβ;ProteinG5a;CaseinKinaseIISubunitβ |
| ProductType | PolyclonalAntibody |
| Properties | |
| Immunogen/Antigen | RecombinanthumanHis-CKIIβproteinpurifiedfromE.coli. |
| Application | WesternBlot(1:2,000) |
| Crossreactivity | Human Mouse Rat |
| PurityDetail | Affinitypurification. |
| Concentration | 1mg/ml |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
ThecaseinkinaseI(CKI)familyofserine/threonineproteinkinasesishighlyconservedfromyeasttohumans.TheCKIfamilyisinvolvedinmanydiverseandimportantcellularfunctions,suchasregulationofmembranetransport,celldivision,DNArepair,circADIanrhythms,andnuclearlocalization.Thenameoftheenzymefamilywasoriginatedfromtheconvenienceofcaseinasasubstratesincetheearliestdaysofresearchonproteinphosphorylation.Caseinkinase2(CK2)isaubiquitous,highlyconserved,essentialserine/threoninekinasewhichhasbeenimplicatedincellcyclecontrol,DNArepair,regulationofthecircadianrhythmandothercellularprocesses.CK2isatetrameroftwoαsubunitsandtwoβsubunits.Theαsubunitshavethecatalytickinasedomain.Lossoftheα‘catalyticsubunitproducesmaleinfertility,andlossofthesingleβregulatorysubunitisearlyembryoniclethal.CK2appearstobeupregulatedinmostcancersandthepromotionoftumOrigenesisbytheoverexpressionofCK2hasbeenreportedintransgenicmice.ParticipatesinWntsignaling.Playsacomplexroleinregulatingthebasalcatalyticactivityoftheαsubunit.
ProductReferences
1)PriceM.A.,(2006)GenesDev.20:399-410.(General)
2)SeldinDCetal.,(2005)MolCellBiochem.274(1-2):63-67.(General)
3)TobinA.B.,(2002)TrendsPharmacolSci.23:337-343.(General)
4)GrossS.D.andAndersonR.A.,(1998)CellSignal.10:699-711.(General)
2)SeldinDCetal.,(2005)MolCellBiochem.274(1-2):63-67.(General)
3)TobinA.B.,(2002)TrendsPharmacolSci.23:337-343.(General)
4)GrossS.D.andAndersonR.A.,(1998)CellSignal.10:699-711.(General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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