当前位置：
首页
>
产品中心 >
Functional_antibody >
Adipogen/anti-Casein Kinase 1 δ, mAb (AF12G4)/YIF-LF-MA0337/100 µl
Adipogen/anti-Casein Kinase 1 δ, mAb (AF12G4)/YIF-LF-MA0337/100 µl
商品编号：
YIF-LF-MA0337
品牌：
Adipogen Inc
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | CKId;HCKID;CSNK1D;CKI-δ;EC=2.7.11.1;EC=2.7.11.26;TaU-proteinKinaseCSNK1D;CaseinKinaseIIsoformδ |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | AF12G4 |
| Isotype | MouseIgG2bκ |
| Immunogen/Antigen | RecombinanthumanHis-CK1dproteinpurifiedfromE.coli. |
| Application | ELISA WesternBlot(1:5,000) Immunoprecipitation(2μl) |
| Crossreactivity | Human Mouse Rat |
| PurityDetail | Ammoniumsulfateprecipitation. |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
CaseinkinasesareagroupofubiquitousSer/Thrkinasesthatphosphorylatekeyregulatoryproteinsinvolvedinthecontrolofcelldifferentiation,proliferation,chromosomesegregation,circADIanrhythms,andmetabolicpathways.CK1familymembersshareahighlyconservedkinasedomainbutdifferintheirvariableN-andC-terminaldomains.Mammalshavesevenfamilymembers:α,β,γ1,γ2,γ3,δ,andε.Theyallshareatleast50%aminoacididentitywithintheproteinkinasecatalyticdomain.CK1isoformsexclusivelyuseATPasphosphatedonorandaregenerallyco-factorindependent.Caseinkinase1δisubiquitouslyexpressedinalltissues,isp53dependentlyinducedinstresssituationsandplaysanimportantroleinvariouscellularprocesses.PKAphosphorylatesCK1δ,predominantlyatSer370invitroandinvivo,andthatsite-specificphosphorylationofCK1δbyPKAplaysanimportantroleinmodulatingCK1δ-dependentprocesses.Caseinkinasesareoperationallydefinedbytheirpreferentialutilizationofacidicproteinssuchascaseinsassubstrates.Itcanphosphorylatealargenumberofproteins.ParticipatesinWntsignaling.Centralcomponentofthecircadianclock.MayactasanegativeregulatorofcircadianrhythmicitybyphosphorylatingPER1andPER2.RetainsPER1inthecytoplasm.
ProductReferences
1)KnippschildUetal.,(2005)CellSignal17(6):675-89.(General)
2)StoterMetal,(2005)Oncogene24(54):7964-75.(General)
3)GiamasGetal,(2007)BiochemJ406(3):389-98.(General)
2)StoterMetal,(2005)Oncogene24(54):7964-75.(General)
3)GiamasGetal,(2007)BiochemJ406(3):389-98.(General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
