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Adipogen/anti-BAFF (mouse), mAb (blocking) (Sandy-2)/AG-20B-0063-C100/100 µg
Adipogen/anti-BAFF (mouse), mAb (blocking) (Sandy-2)/AG-20B-0063-C100/100 µg
商品编号：
AG-20B-0063-C100
品牌：
Adipogen Inc
市场价：
¥7800.00
美元价：
4680.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | BLyS;TALL-1;CD257;BCellActivatingFactor;TNFSF13B |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | Sandy-2 |
| Isotype | MouseIgG1 |
| Source/Host | Purifiedfromconcentratedhybridomatissueculturesupernatant. |
| Immunogen/Antigen | RecombinantmouseBAFF. |
| Application | FunctionalApplication:InhibitionofmouseBAFFbindingtoBAFF-RandTACI(BCMAnottested);blocksBAFFactivityinmice. |
| Crossreactivity | Mouse |
| Specificity | RecognizesmouseBAFF. |
| Purity | ≥95%(SDS-PAGE) |
| PurityDetail | ProteinG-affinitypurified. |
| EndotoxinContent | <0.01eu g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 1mg/ml |
| Formulation | Liquid.InPBScontaining10%glyceroland0.02%sodiumazide. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
BAFFisamasterregulatorofperipheralBcellsurvivaland,togetherwithIL-6,promotesIgclass-switchingandplasmacelldifferentiation.BAFFco-stimulatesactivatedTcells.IncreasedlevelsofsolubleBAFFhavebeendetectedintheserumofpatientswithvariousautoimmunediseases,suchasSjögren’ssyndrome,rheumatoidarthritis,multiplesclerosisandsystemiclupuserythematosus(SLE).FurThermore,BAFFisfoundininflammatorysitesinwhichthereislymphoidneogenesis.BAFFlevelsareelevatedinpatientswithmultiplemyelomaandBcellchroniclymphoidleukemia(B-CCL).
ProductReferences
- TheBcell-stimulatorycytokinesBLySandAPRILareelevatedinhumanperiodontitisandarerequiredforBcell-dependentbonelossinexperimentalmurineperiodontitis:T.Abe,etal.;J.Immunol.195,1427(2015)
- AntibodiesthatblockoractivatemouseBcellactivatingfactoroftheTNFfamily(BAFF)respectivelyinduceBcelldepletionorBcellhyperplasia:C.Kowalczyk-Quintas,etal.; J.Biol.Chem.291,19826(2016)
- Berberinedemonstratesanti-inflammatorypropertiesinHelicobacterpylori–infectedmicewithchronicgastritisbyattenuatingtheTh17responsetriggeredbytheBcell-activatingfactor:X.Wu,etal.;J.Cell.Biochem.aheadofprint2018
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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