脂肪原/抗吸引蛋白，单克隆抗体（9H8）/YIF-LF-MA0146/100µl
商品编号：
YIF-LF-MA0146
品牌：
Adipogen Inc
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | ATRN;DPPT-L;KIAA0548;Attractin;MahoganyHomolog |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | 9H8 |
| Isotype | MouseIgG1κ |
| Immunogen/Antigen | Proteinpurifiedfromhumanplasma. |
| Application | WesternBlot(1:1,000) Immunoprecipitation(1~2μl) |
| Crossreactivity | Human |
| PurityDetail | Ammoniumsulfateprecipitation. |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Attractinisaserumglycoproteinof175kDaandfoundinbothmembrane-boundandsecretedformsasaresultofalternativesplicing.Boththesecretedandmembrane-boundformsofattractinmaybeinvolvedinthedevelopmentandmaintenanceofthecentralnervoussystem.Membrane-boundattractinisaco-receptorforAgouti,antagoNISTofmelanocortin-1receptor.Secretedattractin,expressedbyactivatedTlymphocytesandmodulatesinteractionsbetweenTcellsandmonocytes/macrophages,wasexaminedasapotentialMarkerofimmuneactivity.Attractinmaybeacomponentofapathwayforregulatedproteinturnoverthatalsoinvolvesmahogunin,awide-expressedE3ubiquitinligasefoundatparticularlyhighlevelsinthebrain.Attractinwasconsideredasanextracellulartargetamenableforthedevelopmentofobesity-regulatingdrugs,also.Involvedintheinitialimmunecellclusteringduringinflammatoryresponseandmayregulatechemotacticactivityofchemokines.Mayplayaroleinmelanocortinsignalingpathwaysthatregulateenergyhomeostasisandhaircolor.Low-affinityreceptorforagouti.Hasacriticalroleinnormalmyelinationinthecentralnervoussystem
ProductReferences
1)Duke-Cohan,J.S.,etal,PNAS(1998),vol.95(19):pp.11336~11341.(General)
2)He,L.,etal,NatureGenetics(2001)vol.27:pp.40~47.(General)
3)Duke-Cohan,J.S.,etal,JEnvironPatholToxicolOncol.(2004)vol.23:pp.1~11.(General)
2)He,L.,etal,NatureGenetics(2001)vol.27:pp.40~47.(General)
3)Duke-Cohan,J.S.,etal,JEnvironPatholToxicolOncol.(2004)vol.23:pp.1~11.(General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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