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Adipogen/anti-4-Hydroxy-2-nonenal [4-HNE], mAb (HNEJ-2)/JAI-MHN-020P/20 µg
![Adipogen/anti-4-Hydroxy-2-nonenal [4-HNE], mAb (HNEJ-2)/JAI-MHN-020P/20 µg](https://www.ebiomall.cn/images/adipogen/jai-mhn-ihc-4-hne_stain.jpg)
Adipogen/anti-4-Hydroxy-2-nonenal [4-HNE], mAb (HNEJ-2)/JAI-MHN-020P/20 µg
商品编号：
JAI-MHN-020P
品牌：
Adipogen Inc
市场价：
¥3480.00
美元价：
2088.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | HNEJ-2 |
| Isotype | MouseIgG1κ |
| Source/Host | Ascites |
| Immunogen/Antigen | 4-Hydroxy-2-nonenal(4-HNE)modifiedkeyholelimpethemocyanin. |
| Application | Immunohistochemistry:Recommendedconcentrationis25μg/mL WesternBlot:Recommendedconcentrationis15μg/mL |
| Crossreactivity | All Human |
| Specificity | Recognizes4-HNE-lysine,4-HNE-histidineand4-HNEcysteineadduct.Hasmuchhigheraffinityforthe4-HNE-histidineadductthan4-HNE-lysineor4-HNEcysteineadduct.ShowsalmostnegligIBLereactivitywithproteinsthatweretreatedwithotheraldehydes,suchas2-nonenal,2-hexenal,1-hexanal,4-hydroxy-2-hexenal,formaldehyde,orglutaraldehyde. |
| PurityDetail | Ammoniumsulfatepurified. |
| Formulation | Lyophilized.Contains50mMTris-bufferedsaline(TBS). |
| Reconstitution | Reconstitutewith200μLofdistilledwater. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyJaICA. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. Afterreconstitution,preparealiquotsandstoreat-20°C. |
| Documents | |
| Protocols |  DownloadPDF |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Reactiveoxygenspecies(ROS)areinvolvedinlipidperoxidationinsidethelivingbodies,andmembranelipidsareoneofthemajortargetsofROS.Duringtheperoxidationprocess,avarieryofaldehydesareformed.4-hydroxy-2-nonenal(4-HNE)isanalpha,betaunsaturatedaldehydethatcanbeformedbyperoxidationofomega-6unsaturatedfattyacidssuchaslinoleicacidandarachidonicacid.Especially,4-HNEformedinsidelivingbodyisreportedtooriginatefromphospholipid-boundarachidonicacid.4-HNEmaybeoneofthemostreliablebioMarkeroflipidperoxidation.
ProductReferences
- Themonclonalantibodyspecificforthe4-hydroxy-2-nonenalhistidineadduct:S.Toyokuni,etal.;FEBSLett.359,189(1995)[Westernblot]
- Inductionandnucleartranslocationofthioredoxinbyoxidativedamageinthemousekidney:independenceoftubularnecrosisandsulfhydryldepletion:T.Tanaka,etal.;Lab.Invest.77,145(1997)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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