脂肪原/CD40L(大鼠)(多聚体)(rec.)/AG-40B-0107-3010/3 x 10µg
商品编号:
AG-40B-0107-3010
品牌:
Adipogen Inc
市场价:
¥11800.00
美元价:
7080.00
产品分类:
其它检测试剂盒
公司分类:
Other_kits
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | MultimericCD40L™;ACRP30headless:CD40L;ACRP30headless:CD154;ACRP30headless:TNFSF5;ADIPOQ-CD40L |
ProductType | Protein |
Properties | |
Source/Host | CHOcells |
Sequence | RatCD40L(aa115-260)isfusedattheN-terminustomouseACRP30headless(aa18-111)andaFLAG®-tag. |
Crossreactivity | Human Mouse Rat |
Specificity | Bindstorat,humanandmouseCD40. |
BIOLOGicalActivity | InducesBcellactivation(asdemonstratedbydose-dependentupregulationofCD86). |
MW | ~35-40kDa |
Purity | ≥95%(SDS-PAGE) |
EndotoxinContent | <0.02eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.02eu> |
Concentration | 0.1mg/mlafterreconstitution. |
Reconstitution | Reconstitutewith100μlsterilewater. |
Formulation | Lyophilized.ContainsPBS. |
OtherProductData | UniprotlinkQ9Z2V2:CD40L(rat) FLAGisaregisteredtrademarkofSigma-AldrichCo. |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions. |
Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
Documents | |
MSDS | DownloadPDF |
ProductSpecificationSheet | |
Datasheet | DownloadPDF |
MultimericCD40L™isahighactivityconstructinwhichtwotrimericCD40ligandsareartificiallylinkedviathecollagendomainofACRP30.Thisconstructveryeffectivelysimulatesthenaturalmembrane-assistedaggregationofCD40Linvivo.ItprovidesasimpleandequallypotentalternativetoCD40L+enhancercombinations.MultimericCD40L™hasbeenshowntosuppressalum-inducedIL-1βreleaseandcaspase-1activationinadose-,CD40-andtimedependentmanner,withoutaffectingBMDM(Bonemarrow-derivedmacrophages)viability.ItalsoeffectivelysuppressedtheinflammasomefunctiontriggeredbyNLRP3activators.Thesecretionofcaspase-1independentinflammatorymediatorshasbeenshowntobeunalteredorevenenhanced.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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