脂肪原/PTACH/CDX-P0063-M025/25毫克
商品编号：
CDX-P0063-M025
品牌：
Adipogen Inc
市场价：
¥8940.00
美元价：
5364.00
产品分类：
临床研究
公司分类：
clinical_research
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | NCH51;Cpd51;S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl]thioisobutyrate |
| ProductType | Chemical |
| Properties | |
| Formula | C20H26N2O2S2 |
| MW | 390.56 |
| CAS | 848354-66-5 |
| Source/HostChemicals | Synthetic. |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Whitecrystals. |
| Solubility | SolubleinDMSO(25mg/ml). |
| Identity | DeterminedbyNMR. |
| Declaration | ManufacturedbyChemodex. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | MDYDGUOQFUQOGE-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Non-hydroxamateHDACinhibitor(HDACi)(IC50:32,48and41nMforHDAC4,HDAC1andHDAC6,respectively).Cell-permeableprodrugthatisintracellularlyconvertedtoapotentHDACinhibitor.PredictedtoexhibitasimilarHDACbindingmodeasthatofSAHA,interactingwiththeactive-sitezinctargetinggroup.ShowntoexhibitcomparableantiproliferativeandapoptoticactivityasSAHAagainstvariouscancercelllines.Inhibitsgrowthofvariouscancercellsinvitro(EC50=1.1-9.1μM).AlsoreactivateslatentHIV-1geneexpression.
ProductReferences
(1)T.Suzuki,etal.;J.Med.Chem.48,1019(2005)|(2)T.Sanda,etal.;Leukemia21,2344(2007)|(3)T.Suzuki,etal.;Bioorg.Med.Chem.Lett.17,1558(2007)|(4)A.F.Victoriano,etal.;FEBSLett.585,1103(2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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