脂肪素/PTACH/CDX-P0063-M005/5毫克
商品编号:
CDX-P0063-M005
品牌:
Adipogen Inc
市场价:
¥2240.00
美元价:
1344.00
产品分类:
临床研究
公司分类:
clinical_research
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | NCH51;Cpd51;S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl]thioisobutyrate |
ProductType | Chemical |
Properties | |
Formula | C20H26N2O2S2 |
MW | 390.56 |
CAS | 848354-66-5 |
Source/HostChemicals | Synthetic. |
PurityChemicals | ≥95%(HPLC) |
Appearance | Whitecrystals. |
Solubility | SolubleinDMSO(25mg/ml). |
Identity | DeterminedbyNMR. |
Declaration | ManufacturedbyChemodex. |
OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
InChiKey | MDYDGUOQFUQOGE-UHFFFAOYSA-N |
ShippingandHandling | |
Shipping | AMBIENT |
ShortTermStorage | +4°C |
LongTermStorage | +4°C |
HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | DownloadPDF |
Non-hydroxamateHDACinhibitor(HDACi)(IC50:32,48and41nMforHDAC4,HDAC1andHDAC6,respectively).Cell-permeableprodrugthatisintracellularlyconvertedtoapotentHDACinhibitor.PredictedtoexhibitasimilarHDACbindingmodeasthatofSAHA,interactingwiththeactive-sitezinctargetinggroup.ShowntoexhibitcomparableantiproliferativeandapoptoticactivityasSAHAagainstvariouscancercelllines.Inhibitsgrowthofvariouscancercellsinvitro(EC50=1.1-9.1μM).AlsoreactivateslatentHIV-1geneexpression.
ProductReferences
(1)T.Suzuki,etal.;J.Med.Chem.48,1019(2005)|(2)T.Sanda,etal.;Leukemia21,2344(2007)|(3)T.Suzuki,etal.;Bioorg.Med.Chem.Lett.17,1558(2007)|(4)A.F.Victoriano,etal.;FEBSLett.585,1103(2011)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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