![脂肪原/双泛素[Ub2]（K48连接）（人类）（受体）（TAMRA Pos1）/AG-40T-0238-C050/50µg](https://www.ebiomall.cn/images/adipogen/adipogen_logo_bw_2.png){kind=logo}
脂肪原/双泛素[Ub2]（K48连接）（人类）（受体）（TAMRA Pos1）/AG-40T-0238-C050/50µg
商品编号：
AG-40T-0238-C050
品牌：
Adipogen Inc
市场价：
¥8740.00
美元价：
5244.00
产品分类：
临床研究
公司分类：
clinical_research
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | Twohumanubiquitin(AccessionNr.P0CG47)covalentlylinkedthroughanisopeptidebondatK48residueofoneubiquitinmoleculeandtheC-terminalglycineresidueofanotherubiquitinmoleculeandconjugatedtoTAMRA. |
| Crossreactivity | Human |
| Label/Conjugates | TAMRA |
| Formulation | Liquid.In50mMHepespH7.5,150mMNaCl,2mMDTT. |
| OtherProductData | Use:Linkage-specificdi-ubiquitinisasubstrateforenzymesthatcleavetheisopeptidelinkagebetweentwoubiquitinmolecules.ThisFRET-basedDUBsubstratewithisopeptidebondsbetweenubiquitinmoietiesissuperiortogeldensitometryassays.SinceDUBsrecognizeandcleavesubstrateswithspecificstericconditions,eachsubstratevariesinthepositionofthefluorophoreandquencherandmustbeempiricallytestedforindividualenzymes.Idealforuseasasubstrateforubiquitin-specifichydrolaseswithactivitytowardK48linkages.Werecommendanassaybufferconsistingof50mMHepespH7.5,150mMNaCl,2mMDTT.Fluorescencecanbemonitoredwithanexcitationwavelengthof544nMandanemissionwavelengthof572nM.Reactionconditionswillneedtobeoptimizedforeachspecificapplication.Werecommendaninitialproteinconcentrationof100-500nM. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. Protectfromlight. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Withapredictedmolecularweightof17kDa,di-ubiquitiniscomposedoftwoubiquitinmonomersthatarecovalentlylinkedthroughanisopeptidebond,whichtypicallyformbetweenalysineresidueofoneubiquitinmoleculeandtheC-terminalglycineresidueofanotherubiquitinmolecule.Eachhumanubiquitinmonomeris76aminoacids(aa)inlengthandshares96%and100%aaidentitywithyeastandmouseubiquitin,respectively.Ubiquitinhassevenlysineresiduesthatcanparticipateintheformationofpoly-ubiquitinchains.Thespecificlysineresidueusedinubiquitinconjugationisthoughttodeterminethefunctionofpoly-ubiquitinationincellularprocessessuchasproteindegradation,signalingandtrafficking.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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