脂肪原/相扑结合肽底物(生物素)/AG-CP3-0018-C020/20µg
商品编号:
AG-CP3-0018-C020
品牌:
Adipogen Inc
市场价:
¥3540.00
美元价:
2124.00
产品分类:
其他试剂
公司分类:
Other_reagents
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | SmallUbiquitin-likeModifiersPeptideSubstrate |
ProductType | Chemical |
Properties | |
MW | 1.53kDa |
PurityChemicals | ≥95%(HPLC) |
Appearance | Whitelyophilizedpowder. |
Solubility | Solubleinwaterorotheraqueousbuffers(5mg/ml). |
Formulation | Lyophilized. |
Crossreactivity | Multi-species |
Declaration | ManufacturedbyBostonBiochem |
OtherProductData | Use:ContainsasumoylationconsensussequenceandcanbecovalentlyconjugatedtoSUMO-1,SUMO-2andSUMO-3proteinsinthepresenceoftheE1activating(SAE1/SAE2)andUbcH9conjugatingenzymes.Thebiotingroupallowsforconvenientandsensitivedetectionwithavidin-linkedreagents.Addstocktoinvitroorinvivoassaysatdesiredconcentration.Recommendedconcentrationrangeis50-100μMdependingonconditions. |
ShippingandHandling | |
Shipping | AMBIENT |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
Documents | |
MSDS | DownloadPDF |
ProductSpecificationSheet | |
Datasheet | DownloadPDF |
Smallubiquitin-likeModifiers(SUMOs)areafamilyofsmall,relatedproteinsthatcanbeenzymaticallyattachedtoatargetproteinbyapost-translationalmodificationprocesstermedSUMOylation.TherearefourknownSUMOs(SUMO1-4).AllSUMOproteinsshareaconservedubiquitindomainandaC-terminaldiglycinecleavage/attachmentsite.FollowingcleavageofaC-terminalprosegment,theC-terminalglycineresidueofSUMOisenzymaticallyattachedtoalysineresidueonatargetprotein.Inhumans,SUMOisconjugatedtoavarietyofmoleculesinthepresenceoftheSAE1/UBA2SUMO-activating(E1)enzymeandtheUBE2I/Ubc9SUMO-conjugating(E2)enzyme.Inyeast,theSUMO-activating(E1)enzymeisAos1/Uba2p.SUMOylationcanoccurwithouttherequirementofaspecificSUMOligase(E3),whereSUMOistransferreddirectlyfromUBE2I/Ubc9tospecificsubstrates.UnlikeSUMO1,whichisusuallyconjugatedtoproteinsasamonomer,SUMO2andSUMO3areknowntoformhighmolecularweightpolymersonproteins.SUMOprecursorprocessinganddeconjugationarecatalyzedbyafamilyofcysteineproteasesknownasSUMO-specificproteases(SENPs)andDeSUMOylatingIsopeptidase1.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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