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当前位置: 首页 > 产品中心 > Other_reagents > 脂肪原/相扑结合肽底物(生物素)/AG-CP3-0018-C020/20µg
商品详细脂肪原/相扑结合肽底物(生物素)/AG-CP3-0018-C020/20µg
脂肪原/相扑结合肽底物(生物素)/AG-CP3-0018-C020/20µg
脂肪原/相扑结合肽底物(生物素)/AG-CP3-0018-C020/20µg
商品编号: AG-CP3-0018-C020
品牌: Adipogen Inc
市场价: ¥3540.00
美元价: 2124.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsSmallUbiquitin-likeModifiersPeptideSubstrate
ProductTypeChemical
Properties
MW1.53kDa
PurityChemicals≥95%(HPLC)
AppearanceWhitelyophilizedpowder.
SolubilitySolubleinwaterorotheraqueousbuffers(5mg/ml).
FormulationLyophilized.
CrossreactivityMulti-species
DeclarationManufacturedbyBostonBiochem
OtherProductDataUse:ContainsasumoylationconsensussequenceandcanbecovalentlyconjugatedtoSUMO-1,SUMO-2andSUMO-3proteinsinthepresenceoftheE1activating(SAE1/SAE2)andUbcH9conjugatingenzymes.Thebiotingroupallowsforconvenientandsensitivedetectionwithavidin-linkedreagents.Addstocktoinvitroorinvivoassaysatdesiredconcentration.Recommendedconcentrationrangeis50-100μMdependingonconditions.
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAliquottoavoidfreeze/thawcycles.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
Smallubiquitin-likeModifiers(SUMOs)areafamilyofsmall,relatedproteinsthatcanbeenzymaticallyattachedtoatargetproteinbyapost-translationalmodificationprocesstermedSUMOylation.TherearefourknownSUMOs(SUMO1-4).AllSUMOproteinsshareaconservedubiquitindomainandaC-terminaldiglycinecleavage/attachmentsite.FollowingcleavageofaC-terminalprosegment,theC-terminalglycineresidueofSUMOisenzymaticallyattachedtoalysineresidueonatargetprotein.Inhumans,SUMOisconjugatedtoavarietyofmoleculesinthepresenceoftheSAE1/UBA2SUMO-activating(E1)enzymeandtheUBE2I/Ubc9SUMO-conjugating(E2)enzyme.Inyeast,theSUMO-activating(E1)enzymeisAos1/Uba2p.SUMOylationcanoccurwithouttherequirementofaspecificSUMOligase(E3),whereSUMOistransferreddirectlyfromUBE2I/Ubc9tospecificsubstrates.UnlikeSUMO1,whichisusuallyconjugatedtoproteinsasamonomer,SUMO2andSUMO3areknowntoformhighmolecularweightpolymersonproteins.SUMOprecursorprocessinganddeconjugationarecatalyzedbyafamilyofcysteineproteasesknownasSUMO-specificproteases(SENPs)andDeSUMOylatingIsopeptidase1.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。