脂肪原/锌-α-2-糖蛋白（人类）（rec.）（未标记）/AG-40B-0146-C050/50µg
商品编号：
AG-40B-0146-C050
品牌：
Adipogen Inc
市场价：
¥9600.00
美元价：
5760.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Zn-α-2-GP;Zn-α-2-Glycoprotein;ZAG;ZA2G;AZGP1;ZNGP1 |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | Humanfull-lengthzinc-α-2-glycoprotein(aa21-298)isuntagged. |
| Crossreactivity | Human |
| MW | ~30kDa |
| Purity | ≥95%(SDS-PAGE) |
| EndotoxinContent | <0.1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 10μgsize:0.1mg/mlafterreconstitution. 50μgsize:1mg/mlafterreconstitution. |
| Reconstitution | 10μgsize:Reconstitutewith100μlsterilewater. 50μgsize:Reconstitutewith50μlsterilewater. |
| Formulation | Lyophilized.ContainsPBS. |
| OtherProductData | Uni-ProtlinkP25311:Zinc-α-2-glycoprotein(human) |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Zinc-α-2-glycoprotein(ZAG),firstidentifiedinthe1960s,derivesitsnamefromitsprecipitationfromhumanplasmaupontheadditionofzincsalts.ZAGhassincebeenfoundinsecretoryepithelialcellsandinarangeofbodyfluids.ZAGisidenticaltoalipidmobilizingfactorisolatedfromtheurineofpatientswithcancercachexiaandstimulateslipolysisininvitroandinvivoexperiments.Duetoitsexpressionin,andsecretionfromADIpocytes,ZAGisconsideredanadipokine.RecentlytheclinicalsignificanceofZAGhasbeenclarified.ZAGexpressioninadipocytesisinverselyrelatedtofatmass,thusitisintimatelyinvolvedinthemaintenanceofbodyweightinmiceandhumans.EpidemiologicalstudieshaveuncoveredanassociationbetweenZAGandplasmacholesterol.Thenon-synonymoussinglenucleotidepolymorphismrs4215inZAGisassociatedwithplasmacholesterolandobesity.StructurallyZAGpossessesaclassImajorhistocompatibilitycomplex(MHC)proteinfold.Itisdistinctfromothermembersofthisproteinfamilyinthatitissoluble,ratherthanbeinganchoredtoplasmamembranes,anditassociateswithprolactininducIBLeproteinratherthanβ2-microglobulin.Similartopeptideantigen-presentingclassIMHCmolecules,ZAGpossessesanopenapicalgroovebetweenitsα1andα2domainhelices.
ProductReferences
- Strongandweakzincbindingsitesinhumanzinc-α2-glycoprotein:A.A.Kumar,etal.;FEBSLett.587,3949(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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