脂肪原/20S蛋白酶体激活溶液（100X）/AG-10T-0010-R100/100µl
商品编号：
AG-10T-0010-R100
品牌：
Adipogen Inc
市场价：
¥620.00
美元价：
372.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| ProductType | Chemical |
| Properties | |
| Formulation | Liquid.3%SDS. |
| Crossreactivity | Multi-species |
| Declaration | ManufacturedbyBostonBiochem |
| OtherProductData | Use:Thisbuffercontainstheoptimalformulationfortheactivationofallisoformsofconstitutive20Sandimmuno20Sproteasomeenzymesincludinghuman,rabbit,rat,andmouse.Diluteto1Xforactivationforafinalconcentrationof0.03%inassay.Diluteinreactionbufferspriortoaddingproteasome(donotadddirectlytosolutionsalreadycontainingproteasome).Usewithpeptidesubstratescontainingarginineresiduesisnotrecommended,asprecipitationofthesubstratemayoccur.Intheseinstancesnon-chemicalactivationmayprovidebetterresults. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
The20SProteasomeisthecatalyticcorecomponentofthemulti-complex26SProteasomethatselectivelydegradesintracellularproteins.Itiscommonlyassociatedwithregulatorycomplexes,whichincludethe19SProteasome,thePA28α/βcomplex,orthePA28γcomplex.The20SProteasomeiscomposedof28subunitsarrangedintofourstackedrings.Theouterrings,containingsevensubunitseach,arecomposedofclosely-relatedbutnon-identicalαsubunits.Theamino-terminaltailsoftheαsubunitsformagatethatrestrictssubstrateentryintothecatalyticcore.Theinnerrings,alsocontainingsevensubunitseach,arecomposedofclosely-relatedbutnon-identicalβsubunits.Theamino-terminaltailsofsixoftheβsubunits,threeperring,haveproteolyticactivity.Inhibitionof20SProteasomeproteolyticcoreactivityusingsmallmoleculeinhibitorsisavaluabletoolforthefunctionalstudyofavarietyofproteinsandfortherapeuticintervention.The20SProteasomecanbeactivatedchemicallybytheadditionofdetergentorbytheproteinaceousactivatorPA28Activatorα.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
