脂肪原/USP9x亚型2（人类）（记录）（His）/AG-40T-0545-C025/25µg
商品编号：
AG-40T-0545-C025
品牌：
Adipogen Inc
市场价：
¥9580.00
美元价：
5748.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | ProbableUbiquitinC-terminalHydrolaseFAF-X;DeubiquitinatingeEnzymeFAF-X;FatFacetsinMammals;FAM;UbiquitinThioesteraseFAF-X;Ubiquitin-specific-processingProteaseFAF-X |
| ProductType | Protein |
| Properties | |
| Source/Host | Sf21cells |
| Sequence | HumanUSP9xIsoform2(AccessionNr.Q93008)fusedtoaN-terminalHis-tag. |
| Crossreactivity | Human |
| Formulation | Liquid.InHEPES,NaCl,DTTandGlycerol. |
| OtherProductData | Use:Ubiquitin-specificdeconjugatingenzyme.Reactionconditionswillneedtobeoptimizedforeachspecificapplication.Werecommendaninitialproteinconcentrationof0.05-0.5µM. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
UbiquitinSpecificPeptidase9,X-linked(USP9x),alsoknownasDFFRX,FAFandFAM,isacytoplasmicproteinthatbelongstothepeptidaseC19familyofdeubiquitinatingenzymes.Itis2570aminoacids(aa)inlengthwithapredictedmolecularweightof292.3kDa.HumanUSP9xshares98%aasequenceidentitywiththemouseandratorthologs.USP9xcontainsacatalyticdomainlocatedbetweenaa1531and1971andaubiquitin-likedomainthatislocatedataa873-963.Itiswidelyexpressedandhasbeenshowntointeractwithanddeubiquitinatemultiplesubstrates.Someputativetargetsincludeβ-Catenin,TOR,synuclein-α,theubiquitinligases(E3s)Itch,MARCH7,andSMURF1andtheMAPkinasekinasekinaseASK1.USP9xhasalsobeenshowntocontroltheactivityoftheAMPK-relatedkinasesARK5andMARK4throughdirectremovalofLys29-andLys33-linkedubiquitinchains.Ithasalsobeenshowntopromotecellsurvivalbydeubiquitinatingandstabilizingtheanti-apoptoticproteinMcl-1,andtoregulatechromosomealignmentandsegregationduringmitosisbydeubiquitinatingthechromosomepassengerproteinsurvivin.Additionally,USP9xappearstopromoteTGF-βsignalingviadeubiquitinationofmono-ubiquitinatedSmad4.USP9xexpressionhasbeenshowntobecorrelatedwithseveralcancertypes.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
