当前位置:
首页
>
产品中心 >
Other_recombinant_protein >
Adipogen/Ubiquitin vinyl sulfone (human) (rec.)/SBB-PS0032-C050/50 µg
Adipogen/Ubiquitin vinyl sulfone (human) (rec.)/SBB-PS0032-C050/50 µg
商品编号:
SBB-PS0032-C050
品牌:
Adipogen Inc
市场价:
¥3760.00
美元价:
2256.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
ProductType | Protein |
Properties | |
Source/Host | E.coli |
Sequence | Humanubiquitin(aa1-76)(AccessionNr.P0CG47)withaC-terminalvinylsulfonegroup. |
Crossreactivity | Human |
Application | Typicalworkingconcentrationrangeis1-5μM.Reactionconditionswillneedtobeoptimizedforeachspecificapplication. |
MW | ~9kDa |
Purity | ≥97%(LCMS) |
Concentration | Lotdependent. |
AccessionNumber | P0CG47 |
Formulation | Liquid.In50mMMESpH6.0,100mMsodiumchloride. |
OtherProductData | ClickhereforaTypicalLot-specificProductDatasheetfromtheOriginalManufacturer Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
Declaration | ManufacturedbySouthBayBio. |
ShippingandHandling | |
Shipping | DRYICE |
ShortTermStorage | -20°C |
LongTermStorage | -80°C |
HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | DownloadPDF |
Ubiquitinisasmall(8.5kDa)regulatoryproteinthathasbeenfoundinalmostalltissuesofeukaryoticorganisms.Theadditionofubiquitintoasubstrateproteiniscalledubiquitinationorubiquitylation.Ubiquitinationcanaffectproteinsinmanyways:itcansignalfortheirdegradationviatheproteasome,altertheircellularlocation,affecttheiractivityandpromoteorpreventproteininteractions.Removalofubiquitinfromasubstrateproteinoccursviadeconjugatingenzymes,ofwhichtherearenearly100knownenzymeswithvariouslinkagespecificities.Thisproductconsistsofafull-lengthhuman,matureubiquitinpolypeptide(aminoacids1-76),expressedinE.coliwithaC-terminalwarhead(VinylSulfone).Ubiquitinvinylsulfoneisapotent,irreversIBLeandspecificinhibitorofdeubiquitinatingenzymes(DUBs)basedonaC-terminalelectrophilicvinylsulfonegroup.UbiquitinvinylsulfonecanbeusedforactivityprofilingexperimentsanddeterminingDUBinhibitorspecificity.IttargetsthreeofthefourmajorDUBfamilies:UCH(UbiquitinC-terminalhydrolases),USP(Ubiquitinspecificproteases),OTU(Ovariantumorproteases)andMJD(Machado-Josephindomainproteases)whileJAMMmetalloproteasesarenotinhibited.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
联络我们