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Adipogen/ATG3 (human) (rec.) (His)/AG-40B-0141-3050/3 x 50 µg
Adipogen/ATG3 (human) (rec.) (His)/AG-40B-0141-3050/3 x 50 µg
商品编号:
AG-40B-0141-3050
品牌:
Adipogen Inc
市场价:
¥3600.00
美元价:
2160.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | Autophagy-relatedProtein3;Ubiquitin-like-conjugatingEnzymeATG3;APG3-like;PC3-96 |
ProductType | Protein |
Properties | |
Source/Host | E.coli |
Sequence | RecombinanthumanATG3(aa1-337)fusedtoaHis-tag. |
Crossreactivity | Human |
MW | ~37kDa(SDS-PAGE) |
Purity | ≥95%(SDS-PAGE) |
Concentration | 0.5mg/mlafterreconstitution. |
Reconstitution | Reconstitutein100μlsterilewater.Forlongerstorageadditionof10%glycerolisrecommended. |
Formulation | Lyophilizedfrom20mMTRIS-HCl,pH8.0,containing150mMsodiumchlorideandproteaseinhibitor(SigmaS8830,1xconcentration). |
OtherProductData | NCBIReferenceNM_022488.3:ATG3(human) |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
Documents | |
MSDS | DownloadPDF |
ProductSpecificationSheet | |
Datasheet | DownloadPDF |
ATG3(Autophagy-relatedprotein3;APG3-like;PC3-96)isanubiquitousmemberoftheATG3familyofproteins.Itbelongstotheautophaginproteinfamilyimportantinautophagy,theBIOLOGicalprocesswhichisinvolvedindegradationofendogenousproteinsanddamagedorganelles.ATG3isanE2-likeenzymeinvolvedintheinitialstagesofautophagocytosis,autophagyandmitochondrialhomeostasis.Autophagocytosisisastarvation-inducedprocessresponsIBLeforthetransportofcytoplasmicproteinstothelysosome/vacuole.ItcatalyzesthetransferofATG7-boundATG8(LC3;GATE16;GABA-RAPinmammals)tophosphatidylethanolamine,whichisessentialforautophagy.ItactsasanautocatalyticE2-likeenzyme,catalyzingtheconjugationofATG12toitself.TheATG12conjugationtoATG3playsaroleinmitochondrialhomeostasisbutnotinautophagy.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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