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当前位置: 首页 > 产品中心 > Sandwich_method_ELISA > 脂肪原/虹膜素竞争ELISA试剂盒/AG-45A-0046YTP-KI01/2 x 96孔
商品详细脂肪原/虹膜素竞争ELISA试剂盒/AG-45A-0046YTP-KI01/2 x 96孔
脂肪原/虹膜素竞争ELISA试剂盒/AG-45A-0046YTP-KI01/2 x 96孔
脂肪原/虹膜素竞争ELISA试剂盒/AG-45A-0046YTP-KI01/2 x 96孔
商品编号: AG-45A-0046YTP-KI01
品牌: Adipogen Inc
市场价: ¥19600.00
美元价: 11760.00
产地: 美国(厂家直采)
公司:
产品分类: 夹心法ELISA
公司分类: Sandwich_method_ELISA
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsFibronectinTypeIIIDomain-containingProtein5(cleaved);FibronectinTypeIIIRepeat-containingProtein2(cleaved);FNDC5(cleaved)
ProductTypeKit
Properties
ApplicationSetQuantitativeELISA
SpecificityDetectshumanirisin.Itshouldalsoworkinmouse,ratandmonkeyBIOLOGicalsamples.Doesnotcross-reactwithFNDC4,humanADIponectin,humanNampt,humanRBP4,humanclusterin,humanleptin,humanvaspin,humanGPX3,humanresistin,humanACE2,humanlipocalin-2,humanANGPTL3,humanANGPTL6,humanDNER,humanDLK1,humancalreticulin,humanIL-33,mouseNampt,mouseclusterin,mousevaspinormouseresistin.
CrossreactivityHuman
Monkey
Mouse
Rat
Quantity1x96wells
2x96wells(TwinPlex)
Sensitivity1ng/ml
Range0.001-5μg/ml
SampleTypeCellCultureSupernatant
Plasma
Serum
AssayTypeCompetitive
DetectionTypeColorimetric
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage+4°C
HandlingAdviceAfterstandardreconstitution,preparealiquotsandstoreat-20°C.
Avoidfreeze/thawcycles.
Plateandreagentsshouldreachroomtemperaturebeforeuse.
Use/StABIlity12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox.
Documents
ManualDownloadPDF
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF

Irisinisarecentlydescribedexercise-inducedhormonesecretedbyskeletalmuscleinmiceandhumans.Irisinactivatesbeigefatcells(beigecellshaveageneexpressionpatterndistinctfromeitherwhiteorbrownfatandarepreferentiallysensitivetothepolypeptidehormoneIrisin).IrisiniscleavedfromthetypeImembraneproteinFNDC5andimprovessystemicmetabolismbyincreasingenergyexpenditure.Circulatingirisinlevelswereshowntobeupregulatedafteracuteexercise.Increaseofirisinunderconditionsofobesitymayindicateaphysiologicalfunctiontoimproveglucosetolerance.

ProductReferences
  1. Oxytocinsecretionisrelatedtomeasuresofenergyhomeostasisinyoungamenorrheicathletes:E.A.Lawson,etal.;J.Clin.Endocrinol.Metab.99,E881(2014)
  2. ImplicationofCirculatingIrisinLevelswithBrownAdiposeTissueandSarcopeniainHumans:H.Y.Choi,etal.;J.Clin.Endocrinol.Metab.99,2778(2014)
  3. Irisinlevelsarelowerinyoungamenorrheicathletescomparedwitheumenorrheicathletesandnon-athletesandareassociatedwithbonedensityandstrengthestimates:V.Singhal,etal.;PLoSOne9,e100218(2014)
  4. Circulatingsclerostinandirisinarerelatedandinteractwithgendertoinfluenceadiposityinadultswithprediabetes:T.Klangjareonchai,etal.;Int.J.Endocrinol.2014,ID261545(2014)
  5. Irisin,anovelmyokineisanindependentpredictorforsarcopeniaandcarotidatherosclerosisindialysispatients:M.J.Lee,etal.;Atheroscler.242,476(2015)
  6. Irisinlevelsintheprogressionofdiabetesinsedentarywomen:I.D.Duran,etal.;Clin.Biochem.48,1268(2015)
  7. Theratioofskeletalmusclemasstovisceralfatareaisamaindeterminantlinkingcirculatingirisintometabolicphenotype:Y.C.Hwang,etal.;Cardiovasc.Diabetol.15,9(2016)
  8. ChronicCNSoxytocinsignalingpreferentiallyinducesfatlossinhigh-fatdiet-fedratsbyenhancingsatietyresponsesandincreasinglipidutilization:J.E.Blevins,etal.;Am.J.Physiol.310,R640(2016)
  9. FNDC5expressionandcirculatingirisinlevelsaremodifiedbydietandhormonalconditionsinhypothalamus,adiposetissueandmuscle:B.M.Varela-Rodriguez,etal.;Sci.Reports6,29898(2016)
  10. Eicosapentaenoicacidregulatesbrownadiposetissuemetabolisminhigh-fat-fedmiceandinclonalbrownadipocytes:M.Pahlavanni,etal.;J.Nutr.Bioche.39,101(2017)
  11. Themyokineirisinisreleasedinresponsetosaturatedattyacidsandpromotespancreaticbeta-cellsurvivalandinsulinsecretion:A.Natalicchio,etal.;Diabetes66,2849(2017)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。