Adipogen/anti-Erk1/2, mAb (3A1)/YIF-LF-MA0178/100 µl
商品编号：
YIF-LF-MA0178
品牌：
Adipogen Inc
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | ERT2;ERK1;ERK-1;MAPK3;MAPK3;p44-ERK1;p44-MAPK;EC=2.7.11.24;MAPKinase3;MAPKinaseIsoformp44;Insulin-stimulatedMAP2Kinase;Mitogen-activatedProteinKinase3;ERT1;ERK2;MAPK1;ERK-2;MAPK2;MAPK1;p42-MAPK;MAPKinase1;MAPKinase2;M |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | 3A1 |
| Isotype | MouseIgG1κ |
| Immunogen/Antigen | RecombinanthumanHis-ERK1proteinpurifiedfromE.coli. |
| Application | ELISA WesternBlot(1:2,000) |
| Crossreactivity | Human Mouse Rat |
| PurityDetail | Ammoniumsulfateprecipitation. |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
ERK1andERK2arewidelyexpressedandareinvolvedintheregulationofmeiosis,mitosis,andpostmitoticfunctionsindifferentiatedcells.Manydifferentstimuli,includinggrowthfactors,cytokines,virusinfection,ligandsforheterotrimericguaninenucleotidebindingprotein(Gprotein)-coupledreceptorsandtransformingagents,activatetheERK1andERK2pathways.Whengrowthfactorsbindtothereceptortyrosinekinase,RasinteractswithRaf,theserine/threonineproteinkinase,andactivatesitaswell.Onceactived,Rafphosphorylatestheothertwokinases,MEK1/2,whichinturnphosphorylatestyrosine/threonineinERK1/2.Uponactivation,theERKseitherphosphorylateanumberofcytoplasmictargetsormigratetothenucleus,wheretheyphosphorylateandactivateanumberoftranscriptionfactorssuchasc-FosandElk-1.Involvedinboththeinitiationandregulationofmeiosis,mitosis,andpostmitoticfunctionsindifferentiatedcellsbyphosphorylatinganumberoftranscriptionfactorssuchasELK-1.PhosphorylatesEIF4EBP1;requiredforinitiationoftranslation.Phosphorylatesmicrotubule-associatedprotein2(MAP2).PhosphorylatesSPZ1.Phosphorylatesheatshockfactorprotein4(HSF4).
ProductReferences
1)Smalley,K.(2003)Int.J.Cancer,104,527-532.(General)
2)Johnson,G.L.andLapadat,R.(2002)Science,298,1911-1912.(General)
3)Kolch,W.(2000)Biochem.J.351,289-305.(General)
2)Johnson,G.L.andLapadat,R.(2002)Science,298,1911-1912.(General)
3)Kolch,W.(2000)Biochem.J.351,289-305.(General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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