脂肪原/骨膜蛋白(人)ELISA试剂盒/AG-45B-0004-KI01/96孔
商品编号:
AG-45B-0004-KI01
品牌:
Adipogen Inc
市场价:
¥10600.00
美元价:
6360.00
产品分类:
竞争法ELISA
公司分类:
Competition_law_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications&Handling:
ProductData | |
---|---|
Synonyms | Osteoblast-specificFactor2;OSF-2;Postn |
Properties | |
ApplicationSet | QuantitativeELISA |
Specificity | Detectsnaturalandrecombinanthumanperiostin.Hasbeentestedonhumanperiostinisoforms1and2(shouldalsodetecthumanisoforms3and4). |
Crossreactivity | Human |
Quantity | 1x96wells |
Sensitivity | 15pg/ml |
Range | 78to5000pg/ml |
SampleType | CellCultureSupernatant,Plasma,Serum |
AssayType | Sandwich |
DetectionType | Colorimetric |
ProductType | Kit |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | +4°C |
HandlingAdvice | Afterstandardreconstitution,preparealiquotsandstoreat-20°C.Avoidfreeze/thawcycles.Plateandreagentsshouldreachroomtemperaturebeforeuse. |
Use/StABIlity | 12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox. |
Documents | |
Manual | Download |
MSDS | Download |
RelatedProducts | |
Description:
Periostinisa90-kDamatricellularproteinthatconsistsofatypicalsignalsequence,followedbyacysteine-richregion,anEMIdomain(protein-proteininteractions),fourtandemfasciclin-likedomainsthatareresponsIBLeforintegrinbinding,andaC-terminalregion.Periostinwasoriginallyisolatedasanosteoblast-specificfactorthatfunctionsasacelladhesionmoleculeforpre-osteoblastsandinosteoblastrecruitment,attachmentandspreADIng.PeriostinisalsoinvolvedinmanyfundamentalBIOLOGicalprocessessuchascellproliferation,cellinvasionandangiogenesis.Periostinexpressionisincreasedbybothtransforminggrowthfactorβ1(TGF-β1)andbonemorphogeneticprotein2(BMP-2).Changesinperiostinexpressionarecommonlydetectedinvariouscancersandpre-cancerousconditions,andperiostinmaybeinvolvedinregulatingcancercellactivitiesthatcontributetotumOrigenesis,cancerprogressionandmetastasis.Periostinup-regulationincancersusuallycorrelateswithaggressivenessand/orpoorsurvival.Periostinhasshowntobeinvolvedinmanyaspectsofallergicinflammation,suchaseosinophilrecruitment,airwayremodeling,developmentofaTh2phenotypeandincreasedexpressionofinflammatorymediators.ItisevaluatedasabioMarkerforbronchialasthmaandairwayinflammation.品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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