脂肪原/IL-37(人)ELISA试剂盒/AG-45A-0041YEK-KI01/96孔
商品编号:
AG-45A-0041YEK-KI01
品牌:
Adipogen Inc
市场价:
¥12800.00
美元价:
7680.00
产品分类:
竞争法ELISA
公司分类:
Competition_law_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications&Handling:
ProductData | |
---|---|
Synonyms | Interleukin-1FamilyMember7;IL-1F7;FIL1zeta;IL-1X;Interleukin-1Homolog4;IL-1H4;Interleukin-1zeta;IL-1zeta;IL-1RP1;IL1F7;FIL1Z,IL1H4,IL1RP1 |
Properties | |
ApplicationSet | QuantitativeELISA |
Specificity | DetectshumanIL-37(monomericanddimericforms).Doesnotcross-reactwithhumanIL-33,IL-38,IL-6,IL-23,IL-24ormouseIL-33andIL-38. |
Crossreactivity | Human |
Quantity | 1x96wells 2x96wells(TwinPlex) |
Sensitivity | 10pg/ml |
Range | 0.016to1ng/ml |
SampleType | Plasma,Serum |
AssayType | Sandwich |
DetectionType | Colorimetric |
ProductType | Kit |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | +4°C |
HandlingAdvice | Afterstandardreconstitution,preparealiquotsandstoreat-20°C.Avoidfreeze/thawcycles.Plateandreagentsshouldreachroomtemperaturebeforeuse. |
Use/StABIlity | 12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox. |
Documents | |
Manual | Download |
MSDS | Download |
RelatedProducts | |
Description:
IL-37(IL-1F7;IL-1H4)isanIL-1familymemberthatisexpressedonlyincertaintypesofhumanorgansandcellssuchasheart,thymus,testis,kidney,mononuclearcells(PBMCs)anddendriticcells.IL-37isaninhibitorofinnateimmunitywithanti-inflammatoryproperties.Itbindstotheinterleukin-18receptor(IL-18R)anditsco-receptorSIGIRR.IL-37issecretedasafull-lengthandasaprocessedformstartingfromaminoacidVal46.Itplaysanimportantroleasalinkbetweeninnateandadaptiveimmunityandactsasaninhibitorofautoimmunediseasesandtumorgrowth.IL-37alsoinhibitedLipopolysaccharide(LPS)-inducedimmunologicalreactionandLPS-inducedosteoclastformationandboneresorption.ArecentstudyindicatesthatIL-37proteinformsahead-to-headhomodimerandthisstructurelimitsitsbioactivity.Variantswithmutationsconvertingthecytokineintoamonomericformare13foldmoreactivethanthedimericIL-37.品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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