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Adipogen/IL-36γ (human) ELISA Kit/AG-45B-0008-KI01/96 wells
Adipogen/IL-36γ (human) ELISA Kit/AG-45B-0008-KI01/96 wells
商品编号:
AG-45B-0008-KI01
品牌:
Adipogen Inc
市场价:
¥11800.00
美元价:
7080.00
产品分类:
竞争法ELISA
公司分类:
Competition_law_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Specifications&Handling:
ProductData | |
---|---|
Synonyms | Interleukin-1FamilyMember9;IL-1F9 |
Properties | |
ApplicationSet | QuantitativeELISA |
Specificity | DetectsnaturalandrecombinanthumanIL-36γ. |
Crossreactivity | Human |
Quantity | 1x96wells |
Sensitivity | 3pg/ml |
Range | 3.9to250pg/ml |
SampleType | CellCultureSupernatant,Serum |
AssayType | Sandwich |
DetectionType | Colorimetric |
ProductType | Kit |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | +4°C |
HandlingAdvice | Afterstandardreconstitution,preparealiquotsandstoreat-20°C.Avoidfreeze/thawcycles.Plateandreagentsshouldreachroomtemperaturebeforeuse. |
Use/StABIlity | 12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox. |
Documents | |
Manual | Download |
MSDS | Download |
RelatedProducts | |
Description:
IL-36α(IL-1F6),IL-36β(IL-1F8)andIL-36γ(IL-1F9)aremembersoftheIL-1cytokinefamilythatbindtoIL-36R(IL-1Rrp2)andIL-1RAcP,activatingsimilarintracellularsignalsasIL-1andareinhibitedbyIL-36Ra.TheexpressionofIL-36cytokinesoccursmainlyinthelungandskinandcanbederivedfromdiverseepithelialcelltypesincludingkeratinocytes,bronchialepitheliumaswellasmacrophages,monocytesanddifferentTcellsubsets.IL-36familymembersinducetheproductionofpro-inflammatorycytokines,includingIL-12,IL-1β,IL-6,TNF-αandIL-23,thuspromotingneutrophilinflux,dendriticcell(DC)activation,polarizationofThelpertype1(Th1)andIL-17-producingTcells(αβTcellsandγδTcells)andkeratinocyteproliferation.InductionofIL-36γinmacrophagesuponM.tuberculosisinfectionanditsroleinthereleaseofantimicrobialpeptideshasbeenproposed.IL-36γisalsoinducedinthelunginvariousmodelsofasthmaandcanbeproducedbybronchialepithelialcellsinresponsetoviralinfection,smokeorinflammatorycytokinesandplaysanimportantroleinasthmaticpulmonaryinflammation.IL-36γmightbeapotentialbioMarkerofInflammatoryBowelDiseaseandishighlyexpressedininflamedskinfrompsoriasispatientsandinAllergicContactDermatitis.IL-36γserumlevelsareenhancedandcorrelatetopsoriasisseverityandresponsetotreatmentwithanti-TNF.品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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